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General pharmacology studies the classification of drugs, types of pharmacotherapy, rules for prescribing drugs in prescriptions, routes of drug administration into the body, general patterns of pharmacodynamics and pharmacokinetics of drugs, criteria for the effectiveness and safety of dosing drugs, as well as the rules for the interaction of drugs with each other and other biologically active components. SUBJECT AND OBJECTIVES OF PHARMACOLOGY Pharmacology is the science of the interaction of medicinal substances with the human body, which studies the conditions, processes and consequences of the effects of medicinal substances and other biologically Buy Abana 60caps online - Herbals active compounds on living organisms. Pharmacology comes from two Greek words pharmacon - medicine, poison and logos - teaching. Pharmacology studies the features of the control of living organisms, organs and tissues with the help of biologically active compounds and occupies a special position among the sciences of wildlife. Being an area of active information exchange between the natural science basis of medicine (in the study of biology, chemistry, physiology, Latin) and special medical clinical disciplines, pharmacology allows you to combine and use the achievements of sciences for mutual ...

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Soft dosage forms Soft dosage forms include: ointments, pastes, liniments, suppositories, etc. Ointments (Unguenta) Ointments are non-dose dosage forms, therefore, in prescriptions they are prescribed in total. Only in exceptional cases, when prescribing substances with a pronounced resorptive effect in ointments, ointments are prescribed divided into doses. There are simple and complex ointments, consisting of one or more active ingredients, respectively. Currently, most ointments are produced by the pharmaceutical industry in finished form, they are prepared according to official - online Buy Altace Blood 1,25mg, prescriptions 10mg 5mg, 2,5mg, (Ramipril) Pressure and are prescribed only in an abbreviated form without indicating their composition and concentration of medicinal substances. The prescription begins with the indication of the dosage form (Ung.). All complex and simple unofficial ointments made in pharmacy conditions are prescribed only in expanded form. The recipe lists all the ingredients of the ointment - the active substance, the ointment base; indicate their number; the recipe ends with the prescription of Mfung. (Misce ut fiat unguentum - mix to form an ointment), then DS Eye ointments are prescribed similarly in an amount of not more than 5.0-10.0 g. In ...

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For codeine, WFD (VVD) = 0.1 (0.3) g, herb adonis spring (list B) VFD (VVD) = 1.0 (5.0) g. In the recipe, a single dose of codeine is 0.01 g, daily 0.03 g, for Adonis - 0.5 (1.5) g, doses are not overestimated. The patient will receive 1 tablespoon of medicine - 15 ml, and 180 ml is needed for 12 doses (15 ml ? The ratio of Adonis herb and ready-made infusion is 1:30, therefore, spring Adonis herb must be taken 6.0 g (180?30 = 6.0). Codeine phosphate for 12 doses - 0.12 g, and sodium bromide 0.5 ? Answer: A correctly written prescription looks like this: Rp.: Inf. Adonidis vernalis 6.0 - 180 ml Codeini phosphatis 0.12 Natrii bromidi 6.0 MDS 1 tablespoon 3 times a day. Calculation of doses in drops Example 8 Write out 5 ml of 1% solution of tropicamide. Assign as eye drops 1 drop in both eyes twice for 5 minutes 1 time per day. Calculate the daily dose of tropicamide for the patient. Calculation of the amount of the substance: in 5 ml of a 1% solution, 1 g of the substance is contained in 100 ml; 0.1 g of the substance is contained in 10 ml; 0.05 g of tropicamide is contained in 5 ml of solution. Under standard conditions, 20 drops of an aqueous solution occupy a volume of 1 ml, therefore, 2 drops (0.1 ml) contain 1 mg of the substance. When instilled in both eyes, the dose is ...

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Indirect action occurs as a consequence of the influence of a medicinal substance, secondarily, indirectly in the formation of a specific pharmacological effect. For example, sympatholytics (reserpine) disrupts the synthesis and release of the mediator from the presynaptic membrane. Anticholinesterase agents (neostigmine methyl sulfate) inhibit the enzyme acetylcholinesterase, preventing enzymatic hydrolysis of the acetylcholine mediator. The diuretic effect of cardiac glycosides (cardiotonic drugs) is associated with an increase in heart function, improved blood circulation and normalization of kidney function. The selective action of medicinal substances is due to their affinity for the receptor or organ and depends on the chemical structure of the biologically active substance, on the presence of certain functional groups in its structure. For example, cardiac Buy Artane (Trihexyphenidyl) 2mg online - General glycosides health selectively affect the heart muscle, oxytocin - on the smooth muscles of the uterus, salbutamol selectively affects the ? Adrenomimetic epinephrine (binds to all adrenergic receptors), anticholinergic drugs atropine, platifillin (block all types of M-cholinergic receptors indiscriminately) have a non-selective effect. Anesthesia or general anesthetics ...

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According to clinical data, most births begin from 23:00 to 3:00, the least - from 11:00 to 15:00. The timing of childbirth at night can be explained by the Buy Avodart (Dutasteride) 0,5mg activation online - Hair Loss of the posterior pituitary gland during this period and the release of the hormone oxytocin, which stimulates the muscles of the uterus. Hormonal preparations of the adrenal cortex (glucocorticoids) and their synthetic substitutes, taking into account chronopharmacological principles, are rationally used in the morning hours (?8 hours), when the release of natural hormones is increased, which allows you to get the maximum pharmacological effect when using the smallest doses. Along with the fact that many diseases arise as a result of violations of biological rhythms, a certain rhythm was found in the appearance of symptoms of a number of diseases. It is known that circadian rhythms of convulsive seizures are observed in patients with epilepsy: more often seizures occur at 6:00-7:00, at 11:00-12:00 and at 22:00-23:00. They also found seasonal rhythms of exacerbation of seizures. Seasonal fluctuations in the pharmacokinetic processes of drugs are known. In the spring-summer period, the acetylation of sulfonamides in the human body more than doubles, which leads to ...

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A drenoreceptors of various cells and tissues are also heterogeneous. - adrenergic receptors are distinguished (see Table 7.1). , j adrenergic receptors are localized in the vessel wall , their excitation leads to an Buy Brand Premarin (Conjugated Estrogens) 0,3mg, 0,625mg online - Women's increase Health in vascular tone. 2 adrenoreceptors of the brain is accompanied by a decrease in the tone of the vasomotor centers and a decrease in blood pressure. 1 - A drenoreceptors are located in the myocardium, when they are excited, the contraction of the heart increases and becomes more frequent. In the wall of blood vessels, the muscles of the bronchi and uterus, there are ? 7.5), their excitation is accompanied by a decrease in the tone of these organs. Localization of cholinergic receptors and adrenoreceptors Cholinergic receptors M 1 M 2 M 3 Ng Nm CNS; intramural ganglion of the stomach Heart (myocardium, conduction system) Circular muscle, ciliary muscle of the eye; smooth muscles of internal organs; glands Ganglia; adrenal medulla, carotid glomerulus Skeletal muscles Adrenoreceptors ? 3 Radial muscle of the eye; vessels of smooth muscles of organs, skin, kidneys; veins, arterioles; liver, myometrium CNS; peripheral vessels; platelets Heart; jux-taglomerular apparatus ...

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Higher doses for adults under the skin: single - 0.004 g (2 ml of 0.2% solution), daily - 0.012 g (6 ml of 0.2% solution). Release form: powder (for eye drops); eye ointment 3.5%; ampoules of 1 and 2 ml of 0.2% solution for parenteral administration. Higher doses for adults under the skin: single - 0.01 g, daily - 0.02 g. Release form: 1 ml ampoules of 0.1, 0.25, 0.5 and 1% solution. Neostigmine methyl sulfate ( Neostigmini methylsulfas ). Higher doses for adults inside: single - 0.015 g, daily - 0.05 g; under the skin: single - 0.002 g, daily - 0.006 g. Release form: tablets of 0.015 g; ampoules 0.05%, 1 ml. List B Trimedoxime bromide ( Trimedoximi bromidum ). MEANS BLOCKING CHOLINORECEPTERS (CHOLINOBLOCKERS) Anticholinergic (anticholinergic) are drugs that disrupt or stop the interaction of acetylcholine with cholinergic receptors. By blocking cholinergic receptors, they reduce or completely eliminate the transmission of excitation from cholinergic nerves to the executive organs, and also reduce the effect of cholinomimetic and anticholinesterase agents. This group of drugs includes blockers of M-cholinergic receptors and H-cholinergic receptors. M-cholinergic blockers include agents that predominantly block M-cholinergic receptors of cells of internal organs. As a result ...

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