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The formulary system involves the development of profile lists of pharmacy products, consistent with treatment standards and training programs in the field of rational use of drugs. CHAPTER 2 GENERAL FORMULA General formulation - a section of pharmacology on the rules for prescribing various dosage forms in prescriptions in accordance with the order published on May 15, 2007. Order Ministry of Health and Social Development of the Russian Federation dated February 12, 2007 No. 110 “On the procedure for prescribing and prescribing medicines, medical devices and specialized 25mg, 100mg - Buy (Spironolactone) Diuretics Aldactone online medical food products”. Prescription - a written request from a doctor to a pharmacy about the manufacture and dispensing of a drug to a patient, indicating the method of its use and storage conditions. Application to the order of the Ministry of Health and Social Development of Russia dated February 12, 2007 No. Application to the order of the Ministry of Health and Social Development of Russia dated February 12, 2007 No. Application to the order of the Ministry of Health and Social Development of Russia dated February 12, 2007 No. Instructions for filling out the form "Special prescription form for a narcotic drug and psychotropic substance" ...

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, acetylsalicylic acid, glipizide, furosemide, omeprazole, terbinafine, isoniazid, nedocromil, etc.), others have a low affinity for proteins (ofloxacin, procainamide bind by 15-25%; caffeine, digoxin, captopril - by 25-30%, etamsylate, atenolol - by 5-15%) or are practically in a free state. The medicinal substance has a therapeutic (therapeutic) effect only in a free, unbound state; being in a complex with proteins, it undergoes absorption, transport, distribution, deposition and is devoid of pharmacological activity. The interaction of drugs in the process of biotransformation (metabolism), as a rule, is carried out under the action of microsomal liver enzymes. Some drugs are able to change the activity of enzymes and affect pharmacological parameters. With the induction of microsomal liver enzymes [phenobarbital, rifampicin, diazepam, diphenhydramine (diphenhydramine ? ), caffeine], the duration of circulation of co-administered drugs in the blood decreases, their metabolism increases, the excretion of drugs and their metabolites increases, side effects are weakened, but most importantly, they simultaneously decrease therapeutic effect. The opposite effect is exerted by inhibitors of microsomal liver enzymes (cimetidine, indomethacin, chloramphenicol, tetracycline), the ...

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In addition, the effect of sulfonamides, nitrofurans, antimalarial and acetylsalicylic acid is weakened if they are prescribed together with antisecretory drugs that inhibit the secretion of hydrochloric acid in the stomach (ranitidine, famotidine, pirenzepine, omeprazole, lanzaprazole ? Antacids reduce the absorption of many drugs used together, since the contained salts of bismuth, aluminum, calcium and magnesium form non-absorbable complexes. Examples are the simultaneous administration of antacids with chemotherapeutic agents (antibacterial drugs of the tetracycline series, fluoroquinolones, antifungals, anti-tuberculosis drugs). It is undesirable to use antacids simultaneously with gastroprotectors (sucralfate, bismuth tripotassium dicitrate), since the result of the interaction will be a mutual decrease in antiulcer activity. Influence of drugs on the motility of the gastrointestinal tract. The main part of the drug is absorbed in the proximal part of the small intestine. Therefore, the time of onset of the drug effect and its intensity depend on the rate of evacuation of the contents of the stomach. M-anticholinergics (atropine) and narcotic analgesics (morphine, codeine preparations) slow down gastric emptying, which Buy Barilup (Baricitinib) 2mg online - can COVID-19 ...

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Due to stimulation of postsynaptic opioid receptors disrupts the process of depolarization of the postsynaptic membrane and inhibits the activation of interneurons under the action of the mediator. As a result, the transmission of pain impulses at the level of the spinal cord (spinal action) is disrupted. The mechanism of action of narcotic analgesics: NA - norepinephrine; ENK - enkephalin; 5-HT - serotonin; • - opioid receptor When opioid receptors are stimulated in the gray periaqueductal substance and some other parts of the brain stem, the descending antinociceptive system is activated, which has an inhibitory effect on the transmission of pain impulses along the afferent pathways of the spinal cord (supraspinal action). Descending inhibitory influences are carried out with the participation of serotonin and norepinephrine. As a result of the action of narcotic analgesics on the higher parts of the central nervous system, the emotional assessment of pain changes, its perception decreases (even if the feeling of pain persists, it worries the patient less). Among substances that stimulate opioid receptors, there are full opioid receptor agonists (substances that can cause the maximum effect for a given system), partial opioid receptor agonists (substances that always cause an ...

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The drug is administered parenterally (intravenously, intramuscularly, subcutaneously) and orally. The onset of the effect and its maximum severity are noted, respectively, after 2-3 minutes and 15-30 minutes after intravenous administration; 15-30 minutes and 30-60 minutes after intramuscular and enteral administration. Pentazocine ¤ causes an increase in pressure in the pulmonary artery, which increases the preload on the heart, increases the work of the heart. That is why the drug is not recommended for use in myocardial infarction. Pentazocine ¤ is characterized by dysphoria, hallucinations, tachycardia, and increased blood pressure. The drug is contraindicated in bronchial asthma, traumatic brain injury, epilepsy, cholelithiasis and urolithiasis, liver and kidney failure. Restrictions on use: pregnancy, breastfeeding, children's age (up to 1 year). ) belongs to the group of agonists-antagonists of opioid receptors (stimulates k-receptors and is an antagonist of ? Analgesic activity is 5 times greater in relation to morphine. Used for premedication before surgery, during surgery and for postoperative pain relief. To a lesser extent than morphine, depresses respiration, less risk of drug dependence. Butorphanol, like pentazocine ¤ , increases the 750mg 1000mg, online - Buy ...

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To maintain a balanced work of all systems in the human body, preparations from animal raw materials are used. Non- ossified antlers (antlers) of reindeer, spotted deer, Altai deer or red deer are used, from which pantocrine ? With their use, memory and brain function are improved, energy metabolism is activated, and blood pressure is normalized. Under stressful conditions in the body, antioxidant processes are sharply reduced, the number of free radicals and toxic peroxide products increases, leading to damage to cell membranes. Tonic agents have an antioxidant, anti-stress effect, accelerate tissue regeneration, increase emotional and sexual activity. Release form: bottles of 30 and 50 ml; tablets of 50 pieces; ampoules of 1 ml and 2 ml. NOOTROPICS Nootropics are drugs that activate the higher integral activity of the brain, restore disturbed mnestic mental functions and increase the body's resistance to extreme influences. Nootropic drugs (from the Greek noos - thinking, mind, soul; tropos - aspiration) belong to the group of psychotropic drugs with specific mechanisms of action and pharmacological effects. Means enhance microcirculation in the blood vessels of the brain, thereby improving its blood supply. In addition, they stimulate redox processes in brain tissues, ...

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Antitussives are divided into central action agents: codeine, codeine phosphate ? Means of central action Codeine is similar to morphine and has many of its pharmacological properties, most pronounced in its antitussive effect. Codeine reduces the excitability of the cough center. The drug has less pronounced withdrawal syndrome and drug dependence. Codeine does not have an expectorant effect, therefore, when used, sputum stagnation and mechanical blockage of the airways occur, which is dangerous if there is abundant secretion in the airways. It is contraindicated in respiratory failure, children under 2 years of age. As an antitussive, it is used in its pure form and in combination with expectorants. In combination with bromides and hypnotics, it is part of the combined preparations Codterpin ? Ethylmorphine is a synthetic drug similar in chemical structure to morphine. Compared with morphine, it is much less effective as an analgesic, and to a lesser extent it depresses the cough center. The action of ethylmorphine on the cough center is more selective, and side effects are less pronounced. Ethylmorphine is used as an antitussive for severe cough, which usually accompanies diseases of the lungs, upper respiratory tract (bronchitis, tracheitis). It has a local anesthetic ...

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