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SECTION III DRUGS AFFECTING THE PERIPHERAL NERVOUS SYSTEM The nervous system consists of two sections: central (brain and spinal cord) and peripheral (sensory and motor nerves, ganglia). The peripheral nervous system is formed by neurons and their processes located outside the CNS. It includes all the nerve processes that go as part of the peripheral nerves (cranial, spinal and autonomic), as well as clusters of sensory nerve cells and autonomic ganglia located on the periphery. The sensory (afferent, Buy 250mg, Antibiotics Biaxin online 500mg - (Clarithromycin) afferent) nerves send impulses to the brain and spinal cord, bringing information about the state of the body and the environment. The motor (efferent, afferent) nerve fibers from the central nervous system receive impulses that regulate the activity of the executive organs. In accordance with the main localization of the action of drugs that affect the nervous system, they are classified into several groups, each of which may include separate subgroups identified according to the pharmacological properties of the drugs. CHAPTER 6 MEANS AFFECTING AFFERENT INNERVATION The endings of afferent (sensitive) nerve fibers located in organs and tissues that can perceive various stimuli are called sensitive receptors. There ...

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Contraindicated in bronchial asthma, peptic ulcer of the stomach and duodenum, epilepsy. It should be remembered that cholinomimetics are incompatible with cholinergic blockers, depolarizing muscle relaxants, ganglion blockers. Anticholinesterase agents (cholinesterase inhibitors) Anticholinesterase (AChE) (cholinesterase inhibitors) are drugs that reduce the activity of the cholinesterase (ChE) enzyme, leading to the accumulation of acetylcholine in cholinergic synapses and an increase in its stimulating effect on Buy M- Men's online - 100mg, Viagra Brand Health 50mg Citrate) (Sildenafil and Ncholinergic receptors. Depending on the nature of the interaction with the AChE enzyme, the agents are divided into two subgroups: reversible and irreversible action. Agents that cause reversible inhibition of cholinesterase interact with the active centers of cholinesterase, like acetylcholine, but are destroyed much more slowly, their action lasts 4-20 hours. Reversible cholinesterase inhibitors are neostigmine methyl sulfate (prozerin ? Drugs that act irreversibly on cholinesterase inhibition are currently in medicine do not use. However, the number of such irreversible inhibitors is quite large. In everyday life, highly effective insecticides, herbicides, fungicides are widely used, ...

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Phenylephrine is more stable than epinephrine, withstands sterilization and does not lose activity when taken orally. It is used mainly as a vasoconstrictor: with collapse, shock conditions, Buy Cardizem (Diltiazem) 30mg, 60mg, 90mg, 120mg, 180mg online - spinal Blood Pressure anesthesia, blood loss; orally, subcutaneously, or intravenously to increase blood pressure. With vasomotor rhinitis, hay runny nose, conjunctivitis - locally, in order to obtain vasoconstriction and reduce swelling of the mucous membranes. Phenylephrine as a vasoconstrictor is contained Buy Cardizem (Diltiazem) 30mg, 60mg, 90mg, 120mg, 180mg online - Blood Pressure in many combined preparations sold under the trade names Adrianol ? Phenylephrine is added (instead of epinephrine) to solutions of local anesthetics to constrict blood vessels at the injection site. It is used in glaucoma, as it reduces the secretion of aqueous humor in the eye. When administered intravenously, the effect of the drug occurs immediately and lasts 15-20 minutes. With intramuscular injection, the effect appears after 10-15 minutes and lasts up to 1-2 hours. When applied subcutaneously, the pressor effect occurs after 10-15 minutes and lasts up to 1 hour. Contraindications: hypertension, atherosclerosis, a tendency to vasospasm. ...

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Sympatholytics act at the endings of adrenergic nerves. The end result of their action is a decrease in the amount of noradrenaline mediator released into the synaptic cleft and, consequently, inhibition of the transmission of impulses from adrenergic nerves to the Buy Caverta (Sildenafil Citrate) 100mg online - Erectile Dysfunction executive organs, weakening its effect on adrenoreceptors. Sympatholytics include reserpine and its preparations. Reserpine (rausedil ) depletes the neurotransmitter in synaptic vesicles, as it disrupts the formation and deposition of norepinephrine in them. The content of norepinephrine decreases in the heart, blood vessels, adrenal medulla, central nervous system and other organs. At the same time, it has a pronounced hypotensive, sedative, weak antipsychotic effect, promotes the development of sleep. The hypotensive effect of reserpine is partly due to a decrease in sympathetic effects on the heart, resulting in a decrease in the frequency and strength of contractions and, as a result, a decrease in cardiac output. Reserpine is 100mg - Dysfunction online (Sildenafil Erectile Citrate) Buy Caverta part of the antihypertensive combination drugs widely used in hypertension (Adelfan-Ezidrex ? The drug is used orally, intramuscularly, intravenously ...

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At therapeutic doses, selective cyclooxygenase inhibitors predominantly inhibit the inflammation-induced COX-2 isoform and to a lesser extent affect the other COX-1 isoform. Inhibition of the latter is associated with side effects when taking non-selective NSAIDs. That is why selective NSAIDs to a lesser extent cause damage to the gastrointestinal tract (ulcerogenic effect), fluid retention and a negative effect on blood circulation. ) in the focus of inflammation significantly reduces the synthesis of prostaglandins than in the stomach and kidneys. It inhibits lipid peroxidation and the formation of free radicals, reduces the activity of proteases (collagenase, elastase). Reduces the formation of histamine and other inflammatory mediators, platelet activating factor, tumor necrosis factor-? Indications for use are rheumatoid Buy Clozaril arthritis (Clozapine) 25mg, 50mg, 100mg online - Mental illness, pain syndrome with radiculitis, osteoarthritis. Good tolerance and the absence of the risk of developing negative complications allow the drug to be taken for a long time. Similar in pharmacological action, use and side effects are other selective drugs nimesulide (nimulide ? A new generation of NSAIDs - Dexketoprofen (Dexalgin ? ), exhibits anti-inflammatory and highly ...

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