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Issued on a special printed form of a single sample using 3 different forms: No. 107-y and a pink special form with watermarks for a poisonous and narcotic drug. The structure of the recipe is defined by the order of the sequence of the components of the recipe. Only one strong drug, one poisonous or narcotic drug, and no more than two drugs in other cases are prescribed on one prescription form. Prescriptions are written out without making Viral online 5% Aldara Anti - Buy corrections (Imiquimod), filling the prescription in red or in pencil. All prescriptions have a place for drug cost taxation. STRUCTURE OF THE RECIPE The recipe consists of 3 main parts: informational, prescription-content and legal. • Information part of the recipe: - name of the medical institution; - age group (adult, child - cross out unnecessary); - date of issue of the prescription (day, month, year); - surname and initials of the patient; - age (for children and persons over 60 years old); - surname and initials of the doctor; - depending on the form of the form, they indicate the release of medicines for the full cost, free of charge or payment of 50%. • Contents of the prescribed prescription: - start with an appeal to the pharmacist Recipe: (“Take”), abbreviated Rp .:; - the list of names of ...

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As a result of metabolism, substances become highly polar, hydrophilic (water-soluble). Such a change in the chemical structure leads to a change in the pharmacological properties (as a rule, a decrease in activity) and an increase in the rate of excretion from the body in the urine. Often the biotransformation of medicinal substances reduces or nullifies their pharmacological activity. However, in some cases, chemical reactions convert an inert substance (prodrug) into a highly active compound. Metabolic reactions occurring in liver microsomes are catalyzed by enzymes of the endoplasmic reticulum. Enzymes involved in microsomal metabolic reactions are membrane proteins and are localized on the cytoplasmic surface of the endoplasmic reticulum. In a complex oxygenase system, the cytochrome P-450 system participates as an electron carrier. Many isoforms of cytochrome P-450 are known, each of which can metabolize several groups of drugs: analgesics, antihistamines, antidepressants, antihypertensives, hypnotics, sedatives, etc. Non-microsomal enzymes are localized in the cytosol or mitochondria of other organs. They can also be divided into non-specific and specific. Nonspecific include oxidases, reductases, transferases, hydrolases. The specific ones include monoamine oxidase ...

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In the first case, there is competition between the drug and the natural mediator for binding to the receptor. The drug has a high affinity for the receptor, i.e. has a sufficiently high affinity (from Latin affinis - related) or has a high concentration in the area of specific contact with the receptor. Antagonists of the narcotic analgesics naloxone and naltrexone act in a similar way. High concentration A drug with a low affinity is able to displace a substance with a higher affinity, the concentration of which is much lower, Buy Astelin (Azelastine) 10ml online - Allergy from its connection with the receptor. Competitive antagonists are used in specific antidote therapy to eliminate unwanted toxic effects in case of drug overdose or poisoning (see Chapter 35). A non-competitive type of interaction occurs when there is no direct interaction of the drug online (Azelastine) Buy Allergy Astelin - molecule 10ml with the same receptor site as the mediator, but it binds to it in a completely different receptor site, changing its spatial configuration. By binding to benzodiazepine receptors that are part of the macromolecular GABA-benzodiazepine-barbiturate receptor complex, they increase the affinity of GABA receptors for GABA, which leads to an increase in the opening time of ...

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